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Monday, January 4, 2010

DISINFECTANTS cause some bacteria to adapt, thrive

To keep sickness at bay, many of us constantly wash hands and disinfect surfaces. But a new lab study shows one pesky bacterium eats cleaners for breakfast: When disinfectant was applied to lab cultures of the bacteria, they adapted to survive not only the disinfectant but also a common antibiotic.

The research team focused on Pseudomonas aeruginosa, a bacterium responsible for a range of infections in people with weakened immune systems. When the scientists added increasing amounts of disinfectant to P. aeruginosa cultures, the bacteria adapted to survive not only the disinfectant but also the antibiotic called ciprofloxacin.

Here's how: The bacteria were able to more efficiently pump out antimicrobial agents. The adapted bacteria also had a genetic mutation that allowed them to resist ciprofloxacin-type antibiotics specifically. In principle this means that residue from incorrectly dilluted disinfectants left on hospital surfaces could promote the growth of antibiotic-resistant bacteria, research said. What is more worrying is that bacteria seem to be able to adapt to resist antibiotics without even being exposed to them.

Be aware, MRSA, or methicillin-resistant Staphylococcus aureus, has become a deadly and growing problem in hospitals in recent years. And news out this week suggests the country's first case of a highly drug-resistant form of tuberculosis.

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